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Hydrochlorothiazide from the gut. Although there are no adequate and well-controlled studies using hydrochlorothiazide in pregnancy, thiazide diuretics may cause an increased risk of congenital defects. Some of the side effects that may occur while taking Microzide include black, tarry stools blood in urine or stools cough or hoarseness fever or chills joint pain lower back or side pain painful or difficult urination. Lab tests, including kidney function, blood pressure, and electrolyte levels, may be performed while you use Hydrochlorothiazide, check with your doctor. Lab tests, including kidney function, blood pressure, and electrolyte levels, may be performed while you use Hydrochlorothiazide. Hydrochlorothiazide may increase the blood level of the medicine lithium, and this medicine is used to treat high blood pressure. The thiazide class of diuretics, acting on the kidney to reduce sodium reabsorption in the distal convoluted tubule.
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